Endocrine Abstracts

Mrs X (aged 79) had a history of longstanding hypothyroidism (levothyroxine 100 micrograms daily). Her Free T4 (FT4) had been slightly raised with normal TSH until in Dec 2019, where both became elevated (TSH 5.4 mU/l and FT4 29.4 pmol/l). Repeat TFT in January 2020 also showed the same. Mrs X felt well on Levothyroxine, with no thyrotoxic features. Endocrine clinic investigations (October 2020) showed no evidence of assay interference. Alternative diagnoses such as thyrotropi...

Introduction: Autoimmune thyrotoxicosis (AT) affects 2-5% of the Western population. Despite current NICE guidelines recommending radioiodine as first-line treatment for AT, practical considerations such as licensing often prevent this. Typically, anti-thyroid medication (carbimazole or propylthiouracil) is initially offered. Patients are usually counselled that the remission rate following a 12-18 month course of anti-thyroid medication is approximately 50%.<p class="abst...

Background: With advances in radiological technology, the detection of incidentally discovered pituitary abnormalities is increasing, 90% being secondary to pituitary adenomas. Patient morbidity increases when these lesions are large enough to cause hormone insufficiency or visual field defects, highlighting the importance of appropriate management.Aim: To evaluate management of patients with pituitary incidentaloma in accordance with national guidelines...